Green supported silver nanoparticles over modified reduced graphene oxide: Investigation of its antioxidant and anti-ovarian cancer effects

Abstract A green biosynthesis of silver nanoparticles (AgNPs) decorated Mentha longifolia root extract-functionalized graphene oxide (GO) nanohybrid material has been described. Initially, the was coated on GO’s surface. The phytochemicals plant acted as reducing agent for reduction ions and GO to form rGO- /Ag nanocomposite. nanocomposite characterized using FE-SEM, EDX, FT-IR, TEM, elemental mapping, XRD analysis. cells treated with were assessed by 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide assay 48 h about cytotoxicity anti-human ovarian cancer properties normal (HUVEC) human cell lines, i.e., SKOV3 A2780. IC 50 181.2 196.4 µg/mL against A2780cell respectively. viability malignant line reduced dose-dependently in presence After clinical study, can be introduced a novel composite treatment cancer.